8E: Immune Engineering SIG 2
Time: 10:30 AM to 12:30 PM
Description
Over the past decade the focus of many bioengineers and clinicians has been shifting towards "immune engineering" approaches that include but are not limited to engineered biomaterials for vaccines, immunotherapy (immune-modulation), cell and gene therapy, immune microenvironment engineering, and systems immunology. These research areas embrace a comprehensive list of translational immunology-associated problems including chronic infections, autoimmune diseases, aggressive cancers, allergies, etc. The purpose of the Immune Engineering SIG is to bring together emerging ideas and provide a venue for professional interaction to a large number of academic and industrial research groups and scientists working in these areas.
Moderators:
Josh Doloff, Johns Hopkins Whiting School of Engineering
Objectives
10:30 AM. 402. Comparative Analysis of Tonsil Versus PBMC-derived Human Immune Organoids in Long-term Immune Response to Vaccines and Adjuvants.Zhe Zhong1, Andrés García1, JEAN KOFF, MD, MS2, Ankur Singh, Ph.D.1 1Georgia Institute of Technology, 2Emory University School of Medicine
10:45 AM. 403. Synergistic generation of cardiac resident-like macrophages and cardiomyocyte maturation in tissue engineered platforms.Michael Monaghan, B.Eng, PhD1 1Trinity College Dublin
11:00 AM. 404. The aged bone marrow and the onset of hematopoietic stem cell aging in a polyisocyanopeptide hydrogel.Aidan Gilchrist, PhD1 1University of California, Davis
11:15 AM. 405. Immune Organ-on-Chip Reveal Dysregulated Zonal Compartmentalization in Cancer Patients.Zhe Zhong1, Manuel Quiñones Pérez1, Andrés García1, JEAN KOFF, MD, MS2, Ankur Singh, Ph.D.1 1Georgia Institute of Technology, 2Emory University School of Medicine
11:30 AM. 406. Localized Delivery of Encapsulated Cell Therapy for Targeted Modulation in Pulmonary Fibrosis.Kailyn Nunesz1, Samira Aghlara-Fotovat2, Miguel Mendez3, Ravi Ghanta3, Omid Veiseh1 1Rice University, 2Sentinel Biotherapeutics, 3Baylor College of Medicine
11:45 AM. 407. Anatomical location and alloy/surface treatment composition-specific immune responses to metallic implants.Stuart Bauer, B.S., M.S.1, Jessica Stelzel, B.S.1, Valerie Wong1, Allison Horenberg, B.S.1, Peter Kurtz, 2, Jeremy L. Gilbert, 2, Warren Grayson, Ph.D.1, Joshua Doloff, Ph.D.1 1Johns Hopkins University 2 Clemson University
12:00 PM. 408. Glycation of collagen affects osteogenic differentiation of hMSCs and intrafibrillar mineralization.Siyoung Choi1, Lara Estroff1, Claudia Fischbach1 1Cornell University
12:15 PM. 409. Matrix Mechanics Influences Microvascular Senescence and Pro-inflammation.Jiyeon Song, PhD1, Ya Guan1, Connor Amelung1, Sharon Gerecht, PhD1 1Duke University