7G: Novel Materials - Biologically Inspired
Time: 8:00 AM to 10:00 AM
Description
Bioinspiration from nature can be drawn through structural, functional, or organizational properties. With their tunable properties, bioinspired materials can mimic different aspects of natural structures and have shown promise in various clinical applications. For example, they have been used as biomimetic scaffolds in tissue engineering and regenerative medicine to promote tissue healing and integration. In drug delivery, bioinspired materials can be designed for targeted and controlled release, improving efficacy, reducing side effects, and ensuring a consistent therapeutic effect. Additionally, bioinspired materials are utilized in implants and medical devices due to their integration with the body, which reduces the risk of rejection and improves longevity.
While bioinspired materials are cytocompatible, effective, and sustainable compared to traditional materials for clinical applications, there are challenges in clinical translation including regulatory aspects.
Moderators:
Gulden CamciUnal, Univeristy of Massachusetts Lowell
Nasim Annabi, UCLA
Objectives
8:30 AM. 360. Bioinspired and Mechanically Robust Nanostructured Block Copolymer Hydrogels.Arkodip Mandal1, Matthew Davidson2, Abhishek Dhand3, Michael Toney1, Jason Burdick2 1University of Colorado Boulder, 2University of Colorado, Boulder, 3University of Pennsylvania8
8:45 AM. 361. Chemically Modified Rhamnan Sulfate Compounds as Therapeutics for Metabolic Dysfunction-Associated Steatotic Liver Disease.Gregory Callahan1, Amol Vibhute, PhD1, Cassandra Callmann, PhD1, Aaron Baker, PhD1 1University of Texas at Austin
9:00 AM. 362. Liquid-liquid Phase Separating Peptide Condensates for Therapeutic Delivery.Ushasi Pramanik1, Anirban Das1, Elise Brown1, Heather Struckman1, Huihao Wang1, Sam Stealey, PhD2, Macy Sprunger1, Abdul Wasim3, Jonathan Fascetti1, Jagannath Mondal3, Jonathan Silva1, Silviya Zustiak, PhD2, Meredith Jackrel1, Jai Rudra, PhD4 1Washington University in St. Louis, 2Saint Louis University, 3TIFR Hyderabad, 4Washington University in Saint Louis
9:15 AM. 363. Regulating Diabetic Fibroblasts Using Bioinspired Hyaluronan Binding Silk Hydrogels.Amelia Huffer1, Noah Terkildsen2, Lichong Xu3, Roman Shchepin2, Tugba Ozdemir2 1South Dakota School of Mines andTechnology, 2South Dakota School of Mines and Technology, 3Penn State College of Medicine
9:30 AM. 364. Unconventional Biomaterials for Tissue Engineering and Regenerative Medicine.Gulden Camci-Unal, PhD1 1University of Massachusetts Lowell
9:45 AM. 365. Making Synthetic Hydrogels Inspired by Spider Silk.Ruth Ebubechukwu, BS1, E. Thomas Pashuck, PhD2 1Lehigh Universities, 2Lehigh University