7F: Nanomedicine for Targeted Drug Delivery - 2
Time: 8:00 AM to 10:00 AM
Description
This session will emphasize product development and translational nanomedicine, including but not limited to evaluation of product effectiveness in vivo in disease models, nanomedicine manufacturing, and nanomedicine quality control for specific applications. Nanomedicines include colloids and other nanomaterials that have been engineered to target delivery of diverse payloads (such as small molecules, nucleic acids, or biologics) to specific cells or tissues. Targeting approaches may include but are not restricted to cell membrane coating, surface modification, engineering of particle geometry, or engineering other biophysical parameters. Abstracts from academic researchers with translational products or devices are welcomed and abstracts from industry members are especially encouraged.
Moderators:
John Clegg, The University of Oklahoma
Kelly Langert, Loyola University Chicago
Objectives
8:00 AM. 350. Development of Nanomedicines for Targeting and Preventing Pancreatic β-Cell Death.Jubril Akolade, Ph.D.1, Jillian Collins, Ph.D.1, Isaac Crossley1, Ashton Fremin, Ph.D.1, Nikki Farnsworth, PhD1 1Colorado School of Mines
8:15 AM. 351. Peptide-Functionalized Lipid Nanoparticles for Targeted Systemic mRNA Delivery to the Brain.Emily Han, BS1, Michael Mitchell, Ph.D.1 1University of Pennsylvania
8:30 AM. 352. Optimizing nanoparticle geometry to enhance drug delivery to the brain by the intrathecal route.Kha Uyen Dam, BS1, Elena Andreyko, PhD1, Chung-Fan Kuo, PhD1, Oluwatobi Babayemi, BS2, Rachael Sirianni, PhD1 1UMass Chan Medical School, 2Rice University
8:45 AM. 353. Harnessing Dendrimers for Targeted Drug Delivery to Neurons.Anjali Sharma, PhD1, Anubhav Dhull, MS1, Zhi Zhang, PhD2, Rishi Sharma, PhD1, Aqib Iqbal Dar, PhD1 1Washington State University, 2University of Michigan -Dearborn
9:00 AM. 354. Platelet-inspired Intravenous Nanomedicine enabling Injury-Targeted Thrombin Delivery for Hemorrhage Control.Abigail Roeckmann1, Bipin Chakravarthy Paruchuri2, Rohini Sekar2, Danielle Sun2, Dante Disharoon2, Anirban Sen Gupta2 1Case Western Reserve University, 2Case Western Reserve Society
9:15 AM. 355. mRNA-LNP Delivery to the Damaged Spinal Cord.Jacobus Burger1, Daniel Hellenbrand, PhD2, Luke Bolstad3, Amgad Hanna, MD4, William Murphy, PhD5 1University of Wisconsin-Madison, 2University of Wisconsin- Madison, 3University of Wisconsin, 4University of Wisconsin - Madison, 5University of Wisconsin Madison
9:30 AM. 356. Formulation methods for peptide-modified lipid nanoparticles.Katelyn Miyasaki1, Sangwoo Han, Ph.D. Chemical Engineering - University of Seoul, 20221, Ester Kwon, Ph.D. Bioengineering -- University of Washington2, Olivia Carton2, Rebecca Kandell, Ph.D. Bioengineering -- UC San Diego, 20232, Jonathan Gunn2 1University of California San Diego, 2UC San Diego
9:45 AM. 357. Precision-Targeted Stem Cell-Derived Extracellular Nanovesicles for Elastic Matrix Regenerative Repair in Abdominal Aortic Aneurysms (AAAs).Anand Ramamurthi, PhD, FAHA1, Ali Abba Mutah, DVM, MVSc2 1Lehigh University, 2Lehigh University, Bethlehem PA.