7E: Granular & Macroporous Biomaterials for Tissue Engineering 1
Time: 8:00 AM to 10:00 AM
Description
Granular hydrogel materials emerged as a class of biomaterial that provide for well-defined in vitro and in vivo systems with plug-and-play components and tissue-mimicking 3D environments. Granular hydrogels are composed of a slurry of microgel particles that are assembled to form a larger porous structure. Microporous annealed particle (MAP) scaffolds are a subclass of granular hydrogel material with a void space network stabilized by inter-particle chemical bonds. The modular nature of granular hydrogels offers enormous tunability in not only the individual microgel design but also the homogenous or heterogenous microgel assembly into the bulk scaffold. This session will explore current advances in granular hydrogel technology, including MAP scaffolds, for both immune modulation, tissue repair, organ-on-a-chip, and 3D-printing applications
Moderators:
Donald Griffin, University of Virginia
Tatiana Segura, Duke University
Objectives
8:00 AM. 334. Stress Relaxation Rate of Alginate Microgel Scaffolds Affects Myogenic Differentiation.Andrea C Filler1, J. Kent Leach1 1UC Davis Health
8:15 AM. 335. Enzyme Responsive Granular Hydrogels for Tissue Repair Post-Myocardial Infarction.Kendra Worthington1, Chima Maduka, DVM, PhD2, Amy Perry2, Jason Burdick3 1University of Colorado Boulder, 2BioFrontiers Institute, 3University of Colorado, Boulder
8:30 AM. 336. Tuning the Morphological Properties of Granular Hydrogels to Control Lymphatic Capillary Formation.Daniel Montes Pinzon1, Sanjoy Saha1, Angela Taglione1, Donghyun Jeong1, Liao Chen1, Fei Fan1, Hsueh-Chia Chang1, Donny Hanjaya-Putra1 1University of Notre Dame
8:45 AM. 337. Toward a Multicellular, Gelatin-based Granular Hydrogel Model of the Bone Marrow.Brendan Harley, ScD1, Gunnar Thompson, B.S.1 1University of Illinois Urbana-Champaign
9:00 AM. 338. Bioprinting and Microvascular Assembly within PEGNB Granular Materials.Irene Zhang1, Lucia Choi1, Andrew Putnam, Ph.D.1 1University of Michigan
9:15 AM. 339. Dynamic granular hydrogels as an in vitro cancer model.Ellen Frahm1, chun-Yi Chang1, Chien-Chi Lin, Ph.D.1 1Purdue University
9:30 AM. 340. Tuning Mesenchymal Stem Cell Extracellular Vesicle Content Through Extracellular Cues in Microgel Scaffolds.Matthew Jaeschke1, Georgios Tseropoulos1, Nicole Friend1, Mark Young1, Abigail Bole1, Kristi Anseth2 1University of Colorado, Boulder, 2University of Colorado Boulder
9:45 AM. 341. TissueFab® Porous Bioink for the Next Generation of 3D Bioprinting.Vinson Chu1, Elizabeth Aisenbrey1 1MilliporeSigma