6B: Advancing the Hemocompatibility of Biomaterials

Biomaterial surfaces routinely initiate blood coagulation, creating a grand challenge to the development of blood-contacting technologies and the clinical use of cardiovascular devices. Surface designs based on passivation, presentation of bioactive components, or controlled release of anticoagulant and antiplatelet agents are of interest for improving the hemocompatibility of vascular devices for short-term, long-term, and dynamic blood-contacting applications. This symposium will cover the development of new biomaterial design strategies for preventing thrombosis, methods of surface-directed control of cell-surface interactions in the vascular context, in vitro and preclinical models of thrombosis in biomaterials evaluation, as well as fundamental studies of blood-biomaterial interactions.