4B: Antimicrobial Biomaterials 2
Time: 1:30 PM to 3:30 PM
Description
Due to the threat of antibiotic resistance, biofilms, and the risk of implant-associated infections, strategies for pathogen inactivation play an increasingly important role in biomaterials development. Antimicrobial biomaterials, drug delivery systems, and surfaces that eradicate biofilms and prevent biofilm formation can prevent implant failure, improve clinical outcomes, and reduce treatment costs. This session will cover topics related to designing and characterizing biomaterials to control bacterial, viral, and/or fungal responses. Topics relating to the study of biocompatibility of pathogen-resistant surfaces; the selection and use of in vitro and preclinical models of infection; understanding the roles of biomaterials, pathogens, and hosts in biomaterial-associated infections; and the use of the One Health approach to design biomaterials to combat infections that negatively impact human, animal, and environmental health are also invited.
Moderators:
Elizabeth Brisbois, University of Georgia
Zhaowei Jiang, Brown Univeristy
Bingyun Li, West Virginia University
Objectives
1:30 PM. 140. Interrogating Temperature-Modulated Internal Cavitation Effect on Biofilm Removal Using Self-Propelling Antimicrobial Microbubblers.Joo Hun Lee1, Yujin Ahn1, Adam Marcowicz1, Guillermo Monroy1, Stephen Boppart1, Hyunjoon Kong1 1University of Illinois at Urbana-Champaign
1:45 PM. 141. Development of a Nitric Oxide-Releasing Cephalexin-based Hybrid Compound for Enhanced Antimicrobial Efficacy and Biofilm Disruption.SUMIT KUMAR1, Myddelton parker1, Yi Wu2, Hitesh Handa2, Elizabeth J. Brisbois2 1Universiry of Georgia, 2University of Georgia
2:00 PM. 142. Development of an Antimicrobial Bacteriocin-Based Hydrogel for Treating Second-Degree Burns Wounds.Darnell Campbell, B.S.1, Nicole Levi, PhD1 1Wake Forest University School of Medicine
2:15 PM. 143. Dual-Action Prevention of Adherent and Non-Adherent Biofouling via Slippery, Nitric Oxide-Releasing Nanoemulsion-Infused Porous Surfaces.Grace Nguyen1, Aasma Sapkota1, Hitesh Handa1, Elizabeth J. Brisbois1 1University of Georgia
2:30 PM. 144. Metal-Siloxanes Derived Bio-inspired Superhydrophobicity and Nitric Oxide Generation for Antibiofouling Clinical Applications.Annalise Tucker1, Ekrem Ozkan, PhD1, Sarah Wilson1, Arpita Shome, PhD1, Hitesh Handa1, Elizabeth J. Brisbois1 1University of Georgia
2:45 PM. 145. Harnessing nature’s blueprints to design antifouling antimicrobial interactive biointerfaces and synthetic cells.César Rodriguez-Emmenegger1 1Institute for Bioengineering of Catalonia and Catalan Institution for Research and Advanced Studies
3:00 PM. 146. Nanostructured materials as a tool in the fight against hospital-acquired infections.Anna Michalicha1, Karolina Budniak2, Przemyslaw Suchecki2, Michael Kerber3, Malgorzata Lewandowska2, Anna Belcarz1, Agnieszka Krawczynska2 1Medical University of Lublin, 2Warsaw University of Technology, 3University of Vienna
3:15 PM. 147. Antimicrobial Hemostatic Shape Memory Polymer Foams for Infection Prevention in Traumatic Wounds.Ernest Obeng1, Sevde Can1, Nghia Le Ba Thai1, Changling Du2, Katheryn Dong1, Michaela Hall3, Joshua Satalin3, Michaela Kollisch-Singule3, Mary Beth Monroe, PhD2 1BioInspired Syracuse, Syracuse University, 2Syracuse University, 3SUNY Upstate Medical University