1G: Nanomaterials for Immune Modulation
Time: 1:00 PM to 2:30 PM
Description
Nanomaterials for Immune Modulation: Nanomaterials can be modified to target specialized biomolecules, cells and tissues of the immune system. These nanomaterials range from chemically modified macromolecules, peptides, proteins, or other similar materials. This session will focus on developing nanomaterials that modulate immune responses for a range of diseases.
Moderators:
Adam Gormley, Rutgers University
Lisa Volpatti, Northwestern
Emily Henrich, Rice University
Objectives
1:00 PM. 30. Engineered immunomodulatory nanocarriers for localized tolerance induction in allogeneic islet transplantation. John-Paul Pham1, Layla Summers1, MarĂa Coronel1 1University of Michigan
1:15 PM. 31. Systemic Trafficking of mRNA Lipid Nanoparticle Vaccine Following Intramuscular Injection Leads to Generation of Tissue-specific T Cell Responses. Christine Wei, B.S.1, Yining Zhu, M.S.E.1, Xiaoya Lu, M.S.E.1, Kailei Ding1, Hai-Quan Mao, Ph.D.1 1Johns Hopkins University
1:30 PM. 32. Lipid nanoparticle-mediated metabolic reprogramming of dendritic cells for mRNA vaccines. Dongyoon Kim, Ph.D.1, Emily Han, BS1, Michael Mitchell, Ph.D.1 1University of Pennsylvania
1:45 PM. 33. 2D Nanosilicates Loaded with Protein Antigens Enhance Immune Responses. Chih-Yun Liu1, Mark Gibson1, Anirban Das1, Jai Rudra, PhD2, Akhilesh Gaharwar3 1Washington University in St. Louis, 2Washington University in Saint Louis, 3Texas A&M University
2:00 PM. 34. REGvac 2.0: A Microparticle Strategy for Rheumatoid Arthritis Immunotherapy. Jamal Lewis, Ph.D.1, Allen Tu, PhD1 1University of Florida
2:15 PM. 35. Tissue-, cell-, and organelle-specific drug delivery by poly-glucose nanoparticles for cancer immunotherapy. Biplab Sarkar, PhD1, Christopher Rodell, Ph.D.1 1Drexel University